The third generation detection method of virus antigen

Taking into account the advantages of antigen detection, Japan and the US FDA have respectively approved and developed a third-generation detection method for direct detection of viral antigens. Related projects have made breakthrough progress in the past two months. These new-generation antigen detections use the principle of lateral flow immunochromatography. From sample collection to obtaining the test report, it only takes 15-30 minutes. Judging from the published data (Table 2), the minimum detection limit of these products is 113~1000 TCID50/mL. In the initial clinical research, the positive detection rate of these products on nucleic acid-positive samples can reach as high as 96.7%, indicating Its performance may already be able to meet clinical needs. Due to the small number of positive samples used in clinical studies for these products, the detection rate data may have large differences and fluctuations, and more positive samples may need to be included in subsequent studies for verification.