Data show that among the factors of male infertility, semen quality problems account for up to 90%, with insufficient sperm concentration being the main reason. According to the standards of the WHO Laboratory Manual for the Examination and Processing of Human Semen (6th Edition), normal semen concentration must be ≥15 million/ml, and concentrations lower than this can cause infertility. At present, sperm self-testing mainly detects SP10 protein in semen. SP10 protein is a specific protein present in the sperm acrosome, which is closely related to fertilization ability, can promote sperm movement and better combine with eggs. SP10 protein has a certain linear relationship with sperm concentration. By detecting SP10 protein, sperm concentration can be reflected, which assists in the diagnosis of male infertility.
The significance of sperm quality testing
The significance of sperm quality testing is to evaluate male fertility and help diagnose and treat related diseases that may affect fertility. By testing indicators such as sperm count, motility, morphology, survival rate and white blood cell count, doctors can understand the male's reproductive health status and detect potential problems in a timely manner. This is especially important for men who intend to have children, as it can help them improve their fertility success rate or take necessary treatment measures.
What is sperm SP10?
Sperm SP10 (sperm protein-10) is an immunogenic polypeptide present in the acrosome of mature sperm and is polymorphic. Its corresponding antibodies can inhibit sperm from entering the egg, so it plays an important role in the reproductive process.
Detection significance
Detecting the concentration of sperm SP10 protein can be used to assist in the diagnosis of male infertility and observe the treatment effect. Through this test, the quality and vitality of sperm can be evaluated, thereby providing guidance for the fertility plan of couples of childbearing age. In clinical practice, in addition to detecting SP10 protein, indicators such as sperm survival rate, activity rate, deformity rate and total sperm count are usually considered comprehensively to obtain a more comprehensive evaluation.
How to have a SP10 test?
To have a SP10 test, you can use Singclean Human Sperm SP10 Protein Test Kit. This reagent is suitable for qualitative determination of acrosomal enzyme SP10 protein in human semen in vitro. The kit can be used in assisting the diagnosis of male infertility. For professional use only.
For more details of Singclean Human Sperm SP10 Protein Test Kit, please check it.
Allow test cassette, Antigen extraction buffer to equilibrate to room temperature prior to testing.
1. Open the aluminum foil bag and take out the test card.
2. Put the test card on a horizontal table, unscrew the top cap of the diluted sample, and slowly add 3 drops (about 100 μL) of the pre-treated semen sample to the center of the sample hole;
3. Start timing, the reaction results should be observed within 10-15 minutes, and the results are invalid after 15 minutes.
How to improve sperm quality?
1. Quit smoking and limit alcohol consumption: avoid direct damage to sperm caused by nicotine and alcohol.
2. Regular exercise: such as jogging and swimming can promote blood circulation, enhance the body's immunity, and help improve the quality and vitality of sperm.
3. Reduce stress: Long-term excessive stress will affect the endocrine system, which in turn affects sperm quality.
4. Avoid high temperature environment: Being in a high temperature environment for a long time will affect the production and quality of sperm. You should avoid frequent hot springs or wearing tight pants.
5. Get enough sleep: Proper rest and sleep help maintain normal reproductive function.