As the temperature rises and it catches up with the rainy season, the number of mosquitoes around us has gradually increased. Mosquitoes not only bite and suck blood, but also spread a variety of diseases, including dengue fever. May to November each year is the epidemic season for dengue fever in my country, and we must always be vigilant.
So, what is dengue fever, do you really know about Dengue? This article, I will introduce Dengue to you.
What is Dengue?
Dengue fever (DF) is an acute insect-borne infectious disease caused by dengue virus. Due to the severe pain, it is also called "breakbone fever". It is a Class B statutory infectious disease in my country. The peak season for dengue fever is summer and autumn. Generally, the number of cases increases gradually from May, and the peak period is from August to October. The incubation period is 3-14 days, usually 5-9 days, and the whole population is generally susceptible.
Dengue virus enters the human body through the bite of Aedes mosquitoes, and enters the blood circulation after proliferating in the mononuclear phagocyte system, forming the first viremia. Then it is located in the reticuloendothelial system and lymphoid tissue, proliferates to a certain extent in monocytes, macrophages and Kupffer cells of the liver, and enters the blood circulation again, causing the second viremia.
Dengue virus combines with antibodies to form immune complexes, activates the immune system, leads to increased vascular permeability, vascular dilation, congestion, plasma protein and blood formed components extravasation, causing pathological and physiological changes such as hemoconcentration, hemorrhage and shock.
The pathological and physiological changes of severe dengue fever are mainly increased vascular permeability and plasma extravasation, and there is no obvious capillary endothelial cell damage. Plasma extravasation is the main clinical manifestation of severe dengue fever. During the fever-relief period, a large amount of plasma enters the cavity, blood volume decreases, hemoconcentration, and eventually shock.
What is the symptoms of Dengue?
1. Sudden fever
The disease has an acute onset, high fever, and a fever course of 5-7 days. The body temperature may reach 39℃ or above 40℃, extreme fatigue, and may also be accompanied by symptoms such as chills and fear of cold.
2. Pain in various parts of the body
The patient mainly has muscle pain in various parts of the body, often accompanied by pain in the muscles, joints and bones of the limbs and waist.
3. Rash
The rash often appears on the 3rd to 6th day of the course of the disease, mainly maculopapular rash and congestive rash, but there are often needle-sized bleeding spots mixed in, symmetrically distributed on the trunk and limbs, and generally disappear after 3-4 days.
4. Lymph node enlargement
The patient may have superficial lymph node enlargement throughout the body, and may also have tenderness, but the local skin is not red and swollen.
5. Bleeding
The patient may have a tendency to bleed, such as a positive arm tie test, skin petechiae, and some severe cases may also have bleeding in the mouth, gums, digestive tract, abdominal cavity and vagina.
Dengue Fever Prevention Measures
If you are traveling or living in an area where dengue fever is prevalent, please try to avoid mosquito bites, do not wear clothes that expose the skin and use shelter such as curtains and mosquito nets, maintain a clean and dry environment, and consider using mosquito repellent spray. At the same time, timely medical treatment and receiving treatment and guidance from doctors can also help you recover as soon as possible.
In short, as long as timely prevention and treatment are carried out, most dengue fever patients can recover quickly. Therefore, we don't have to worry and panic too much. As long as we stay vigilant and take appropriate prevention and treatment measures, we can successfully cope with the challenges of dengue fever.
And there is currently no vaccine to prevent dengue fever, and there is no specific medicine for treatment. The focus of treatment is to control pain, replenish fluids in time, prevent bleeding, and prevent mosquitoes and isolate as soon as possible.
If you accidentally get infected with the dengue virus, don't panic too much. Dengue patients generally have a good prognosis and can basically recover after timely treatment.
In order to prevent the spread of the disease to family members or others, please cooperate with the dengue fever prevention and control requirements of the local health department.
When staying at home or in hospital for treatment, do a good job of mosquito isolation, including using mosquito nets, screen doors and windows, wearing long-sleeved clothes, spraying mosquito repellents and other measures to reduce unnecessary outdoor activities.
If you have recently traveled to a dengue fever-endemic area and have suspicious symptoms, you need to seek medical attention promptly.
How to detect dengue fever?
1. Routine examination
If you want to test dengue fever, you can do it in a conventional way. If there is peripheral blood dengue fever, the total number of white blood cells will also decrease due to the occurrence of the disease. Especially during the rash period, the number of white blood cells will drop significantly, and the percentage of neutrophils will also decrease. The blood picture will return to normal one week after the fever subsides.
2. Urinalysis
Urinalysis can also be used to preliminarily determine whether dengue fever has occurred. There will be a small amount of protein, red blood cells and white blood cells.
3. Virus isolation test
By extracting blood from the patient's body and isolating the virus, the specificity of the virus can be effectively understood. Virus isolation can be used to determine whether the patient is infected with dengue fever. The condition can also be identified by adding hemagglutination inhibitors.
Also, I recommend Singclean Dengue Test Kit is used for qualitative detection of Dengue virus antigen in human serum, plasma or whole blood by immunochromatography and double-antibody sandwich method. It has the advantages below.
01
Convenient
2 drops of blood for testing
02
Rapid
10 mins to read test result
03
Effective
Able to test 4 types of Dengue
For more details of Singclean Dengue Test Kit and our other IVD products, please feel free to contact promotion@hzxhe.com!